There lies an excised specimen that’s eager on its mystical journey,
Diving deep in formalin that’s geared up on its knock-out tourney,
Like a baby twinkling eyes to see the world and face the trails;
Excited are we ‘Pathologists’ to join the chorus of tell-tales!
Looking through its length and breadth,
A Mirror that reflects the extent of growth;
Downhearted to see the mortal breath of necrosis,
The tumor stepping into a grave prognosis.
The Majestic tumor striking on the glass slide,
A Work of art by Diverse patterns sets the stride,
A rosette like a blooming daisy, or rows as trabeculae,
Disciplined cops stand in palisaded array,
Sheets or fascicles, an amalgam of these never an allay!
Cells as round as moon, as spindle as a stan,
Lays out to solution, one among a million.
Following the pattern of chromatin,
Nucleolus or inclusion added as gratin.
Some tumors meek and mild, others fast and furious,
Subject to histologic type and the tumor grades;
Counting in numbers the mitotic figures,
Atypical ones are the horror triggers!
Riding on its vintage motorcycle, tumor keen on its descent and destiny,
Immunohistochemistry assists on this final testimony;
An endless parade of antigen and antibodies, savors the marker-panel recipe,
Spots the origin, plots the subtype and escorts to the therapy.
On its nomadic voyage, tumor questions its origin,
Am I a motherless mass being called a Sporadic? or
Member of an ancestral family, being called Syndromic?
Am I born of Mutation, amplification or translocation?
Karyotyping, FISH or NGS gives the decision.
We are proud to sign the final report,
Moment of fulfillment beyonds every verdict,
We are the gates between Entry and exit,
A summit where every answers exist!